Metaglucent FAQ: Answers to the Most Asked Questions

A dietary supplement in vegetable capsules, thirty to a bottle, taken as one capsule a day. The panel declares four nutrients with amounts — vitamin C, vitamin D, magnesium and chromium — and then one Proprietary Blend of 528 mg holding thirteen more ingredients with no individual amounts. The front of the bottle reads Diabetes Support Formula.

Seventeen dietary ingredients. Four are printed with a weight: vitamin C 90 mg, vitamin D 25 mcg, magnesium 20 mg and chromium 100 mcg. Thirteen sit inside the blend, in this printed order: turmeric, cocoa bean extract, berberine HCL, gymnema, cassia cinnamon, olive leaf extract, eleuthero root extract, juniper berry, maritime pine bark extract, bitter melon fruit extract, banaba leaf extract, butcher’s broom root extract and guggul resin extract. The other ingredients are a hypromellose capsule shell, microcrystalline cellulose, magnesium stearate, stearic acid and silicon dioxide.

We do not know why, and it is the single most serious question on this label. 21 CFR 101.93(g)(1) defines a disease as damage to an organ, part, structure or system of the body such that it does not function properly, or a state of health leading to such dysfunctioning. Paragraph (g)(2) lists the name of the product among the factors by which FDA judges whether a statement is a disease claim. Diabetes is a named disease. The required FDA disclaimer is printed on the pack, and a disclaimer does not make a disease claim permissible. We print the regulation, the photograph of the front panel and nothing else, because the judgement belongs to a regulator and not to a retailer.

No. No dietary supplement may lawfully claim to treat, cure or prevent a disease, and this one carries the standard FDA disclaimer saying exactly that on the same pack as the phrase on the front. Diabetes is managed by a clinician with monitoring and, for most people, medicine. Nothing sold on this site changes that, and nobody should stop or alter a prescription because of a capsule.

Because the label uses a proprietary blend. Under 21 CFR 101.36(c) a blend declares the total weight of all its dietary ingredients and lists them in descending order of predominance by weight, and individual amounts are not required. It is legal and it is common. It is also why no dose in that 528 mg can be checked against any study.

Ceilings and nothing more. Descending order of weight means the ingredient in position n cannot exceed the total divided by n. Turmeric could be anything up to 528 mg; cocoa up to 264 mg; berberine up to 176 mg; gymnema up to 132 mg; guggul, last of the thirteen, cannot exceed about 41 mg. Those are hard upper bounds, not amounts, and every one of them is consistent with the ingredient being present in a trace.

The four printed nutrients come to about 110 mg of dietary ingredient between them. The blend is 528 mg. So the blend is roughly five sixths of the 638 milligrams of dietary ingredient in this capsule, and it carries one number for all of it.

Yes, all four. We recalculated every one against the FDA’s published Daily Values and they check out: vitamin C 90 mg against a 90 mg DV is 100 per cent; vitamin D 25 mcg against 20 mcg is 125 per cent; magnesium 20 mg against 420 mg is 4.8 per cent, printed as 5; chromium 100 mcg against 35 mcg is 285.7 per cent, printed as 286. That is the most careful arithmetic we have found on any label on this desk.

It is nearly three times the Daily Value, and chromium has no established Tolerable Upper Intake Level, which is a different thing from being proven safe at any dose. The number that matters here is not the percentage but the interaction: the NIH Office of Dietary Supplements states that chromium supplements might have an additive effect with metformin or other antidiabetes medications and thus might increase the risk of hypoglycemia.

Because 20 mg is a small amount against a 420 mg Daily Value. There is a second point worth making: the form here is magnesium oxide, and the NIH notes that magnesium in the aspartate, citrate, lactate and chloride forms is absorbed more completely and is more bioavailable than magnesium oxide. A small amount of the least absorbable common form is not a magnesium supplement in any meaningful sense.

25 mcg is 1,000 IU. The Tolerable Upper Intake Level for adults is 100 mcg, or 4,000 IU, so this capsule sits well under it on its own. If you already take a separate vitamin D supplement, add the two together before you decide, and tell whoever prescribes for you.

It is third by weight in the blend, and it is the ingredient with the widest interaction profile on the panel. Memorial Sloan Kettering’s About Herbs monograph reports that in human studies, repeated oral intake of berberine at a dose used in some studies significantly decreased CYP2D6, 2C9 and 3A4 activity — three enzyme systems that clear a great many common prescription medicines. The same monograph says the benefit studies are of limited quality and that more studies are needed.

It is cassia cinnamon, named on the panel as <i>Cinnamomum cassia</i>. NCCIH notes that interactions between coumarin, a chemical found in cassia cinnamon, and the liver have been reported, and that it is unclear whether cinnamon supplementation is helpful for diabetes or weight loss. With no amount published, there is no way to say how much coumarin a daily capsule delivers.

All three are studied for lowering blood sugar, which is the point of putting them here and also the reason for the caution. Together with berberine, cinnamon and chromium that is six ingredients in one capsule pointing the same direction, for a buyer who may already be taking a prescription that points the same direction. None of the six has a published amount in this blend.

Unknown, and two things work against it. NCCIH says combining curcumin with piperine is one way to improve the bioavailability of curcumin, and there is no piperine anywhere on this panel. And turmeric heads the blend, so its ceiling is 528 mg — but a ceiling is not an amount, and no standardisation percentage is printed either.

Not that we can see. Several ingredients are called an extract, which tells you a concentration step happened, but no percentage of any marker compound is printed for any of them. Without both an amount and a standardisation, even a published milligram figure could not be matched to a trial.

The suggested use panel reads: as a dietary supplement, take one (1) capsule daily. There is no instruction about food, no time of day and no split dose. The caution panel adds: do not exceed recommended dose.

Not published. The label gives no instruction either way. Several ingredients here are ones people commonly take with a meal, but we will not invent a direction the label does not give.

Not published, and we will not invent a timeline. The brief records a most-common wait of four to eight weeks, and that figure comes from the same review block its own source note marks as layout copy, so it is not evidence of anything. What we can say with confidence is the arithmetic: one bottle is thirty days and the guarantee runs sixty, so a first bottle finishes with the refund window half open.

Take the next one at the usual time. Do not double up — the caution panel says not to exceed the recommended dose, and with a blend whose contents have no published amounts, doubling means doubling something you cannot measure.

The label says to store this product in a cool dry place below 30°C, which is 86°F, and the warning panel adds: keep out of reach of children, do not use if the safety seal is damaged or missing, store in a cool dry place.

Not on anything we were given. No expiry or best-before date appears on the label images in the pack, and the brief says the lot and best-before appear on the base of the bottle when the bottle shows it. Check the base of your own bottle when it arrives.

For a healthy adult not taking medicine, nothing on this panel stands out as alarming at the printed amounts. That sentence carries two conditions, and the second one does most of the work: this is a product bought overwhelmingly by people who are taking medicine. The label’s own caution panel says to consult a physician before use, especially if you are taking a medication or have a medical condition, and on this formula that is the operative sentence rather than the boilerplate.

Ask the clinician who manages your diabetes before you buy, not after. This is the firmest line on the site. The NIH states that chromium supplements might have an additive effect with metformin or other antidiabetes medications and thus might increase the risk of hypoglycemia, and there are five further ingredients in this blend studied for lowering blood sugar, all of them at amounts nobody has published.

It may. Berberine is third by weight here and has been reported to significantly decrease CYP2D6, 2C9 and 3A4 activity in human studies, and those enzymes clear a long list of ordinary medicines. NCCIH’s general guidance is blunt: people who take diabetes drugs should tell their health care providers about any herbal supplements they are taking. The same holds for every other prescription.

Two things. The cassia cinnamon, for the coumarin point above, and berberine, which is cleared hepatically. Neither has a published amount. Take the panel to the clinician who manages the condition.

Shakiness, sweating, a racing heart, confusion, irritability or sudden hunger are the commonly described signs, and they are a medical matter rather than a supplement one. If you take medicine that lowers blood sugar and you add something else that may lower it too, that is a conversation with a clinician and, if they advise it, closer monitoring — not a thing to work out from a website.

None are listed on the label, which is not the same as none existing. Digestive upset is the commonly reported effect for berberine and for turmeric at higher intakes. With thirteen ingredients at unpublished amounts, an unexpected effect cannot be traced to a single one of them, which is a practical argument for simpler formulas.

No. The label says it outright: not for use for those under the age of 18 or pregnant or nursing mothers. Berberine additionally carries a specific caution about infants.

No. The label excludes under-18s, and the brief repeats it.

Yes, and this is one badge the panel genuinely supports. The shell is hypromellose, a plant-derived material, and nothing on the other-ingredients line is animal-derived. In a category full of gelatin shells, that is worth noticing.

The listing carries both badges, and nothing in the printed other-ingredients line is a wheat or dairy derivative. No certifying body is named and no test report was published to us, so treat them as plausible and unverified. If you have coeliac disease or a dairy allergy, ask the maker’s desk directly on +1 323-391-7417 before you buy.

The label reads: distributed by Metaglucent, Aurora, CO 80011, USA, with the phone number +1 323-391-7417 and the address [email protected]. Distributed by is not the same as manufactured by, and no manufacturer is named anywhere on the pack.

Themetaglucent, a USA Authorized Metaglucent Retailer. We are a retailer and a review desk, not the manufacturer. Our office is 299 Park Avenue, Floor 21, New York, NY 10171 and returns go to 546 Fifth Avenue, Floor 6, New York, NY 10036.

Yes. Orders placed through the buy buttons on this site earn this site a commission. It changes nothing we have written: the score on this site is 2.8 out of 5, the front-panel problem is the first thing on the home page, and we publish a list of ten things the label does not tell you. A site chasing conversions would not lead with any of it.

No, and nothing in this category is. The FDA states plainly that it does not have the authority to approve dietary supplements before they are marketed. The listing says the facility is FDA-registered, which means the factory is listed with the agency — a registration, not an endorsement, and not a check of what is in the bottle.

No doctor is named on the label, on the listing, or anywhere in the material we were given. We have not invented one to fill the gap. A credential you cannot check is not a credential.

The brief gives lot MET-26/TH-3375 and certificate reference MET-3375-26-TH, and says in its own words that both are draft labels rather than lab proof. No laboratory report sits behind either number, and we have published no test data because none was supplied. To match a number to an order, call +1 (302) 200-3480.

Because the review block in the material we were given is labelled, by its own source note, as layout copy only — star scores, written counts, order counts and named buyers alike. Publishing placeholder text as buyer feedback would be inventing customers. We would rather have an empty reviews page than a fabricated one, so the page explains the gap instead.

Not published to us. Pack prices are whatever the info page prints at checkout, so every pack card on this site says price at checkout and none of them carries a figure. We print no number we have not seen.

If you have never taken it, one bottle. Thirty capsules is thirty days and the guarantee runs sixty, so a single bottle finishes with half the window still open — the most forgiving arithmetic of any product on this desk. Two bottles land exactly on day sixty. Three and six run past the window, so they are commitments made before you have any evidence.

On this site, themetaglucent.com, so the refund window on this order desk applies to your order. Buying elsewhere means a different desk, a different policy and no help from us.

Not published. The brief says orders ship from the United States unless the sales page says otherwise, and that a tracking number arrives in the order email. Cost, speed and international availability were not published to us and we have not guessed at them.

Sixty days from purchase, unless the sales page prints a longer window. Call the order desk on +1 (302) 200-3480 with your order ID to start a claim. It is a purchase policy, not a medical promise — it returns your money, and it does not imply anything about results.

Call +1 (302) 200-3480 with the order ID first. Put your full name, the email on the order and the order ID in with the parcel, send it with tracking to 546 Fifth Avenue, Floor 6, New York, NY 10036, and keep the tracking number. Return shipping is paid by the buyer.

Three to five business days for the desk to credit it after the return is processed, then five to ten days for the money to appear on the card. Those two windows are separate and they add up.

+1 (302) 200-3480 is the order desk: orders, tracking, changes and refunds. +1 323-391-7417 is printed on the label for Metaglucent in Aurora, Colorado, and is for questions about the product itself. They are two different companies. Our own address, [email protected], handles pages, typos, privacy and press — it cannot see your order.

Because the score is the sum of eight honest lines rather than one marketing line. The back of this bottle earns 5 out of 5 for percentage accuracy and 5 for ease of use. The front earns 1 for claim honesty, the blend earns 2 for dose against research, and there are no verified reviews to score. Averaging those gives 2.8. We publish the parts as well as the total so you can disagree with any line of it.

Several things, and they are real. Four nutrients are printed with amounts and all four percentages survive the arithmetic — rarer than it should be. The blend names a plant part and a Latin binomial for every botanical. The capsule is vegetarian. The caution panel is specific rather than decorative. And one capsule a day with nothing to time or split is the easiest regimen we have written up. The care that produced all that simply did not reach the front of the pack.